Overview
The MSA 815366 GM E-P100 combination cartridges are replacement filters engineered for use with MSA Advantage Series respirators. These multigas and P100 particulate cartridges deliver dual-layer protection against both hazardous gases and particulate aerosols in demanding industrial environments. Supplied as a pair (2 cartridges per pack), they feature a lightweight, low-profile design with bayonet-style connectors for quick and secure installation.
Key Features
- P100 HEPA Filtration: 99.97% filtration efficiency against airborne particles 0.3 microns or larger
- Multigas & Vapor Protection: Protection against organic vapors, ammonia, methylamines, formaldehyde, hydrogen fluoride, acid gases including chlorine, hydrogen chloride, sulfur dioxide, chlorine dioxide and escape from hydrogen sulfide
- Bayonet Quick-Change Design: Easy installation with bayonet-style design for quick mounting; low-lug height and lead-in connectors lock into place with a single twist
- NIOSH-Certified: Approved under NIOSH 42 CFR 84
- Metal Construction: Made of metal for easy detection of damage
- Lightweight Design: Lightweight and low-profile for reliable performance
Technical Specifications
- Manufacturer Part Number: 815366
- Manufacturer: MSA (Mine Safety Appliances Co.)
- Filter Rating: P100
- Filter Type: HEPA (High-Efficiency Particulate Air)
- Cartridge Type: Combination (Multigas + Particulate)
- Filter Efficiency: 99.97% at 0.3 micron MMAD
- Connection Style: Bayonet
- Quantity Per Pack: 2 cartridges
- Color: Silver
- Certifications: NIOSH 42 CFR Part 84
- Country of Origin: United States of America
- Protection Classes: AM, CD, CL, FM, HC, HF, HS (Escape only), MA, OV, SD
Typical Applications
These cartridges are ideal for market environments where there are significant particulate hazards, such as utilities, oil and gas, construction, and general industry. The MSA 815366 is commonly used in spray booths, hazmat remediation, confined space entry, chemical handling, and industrial cleanup operations requiring protection against both airborne dust and hazardous vapor exposure.
Compatibility & Replacements
Compatible With
- MSA Advantage 200LS Half-Mask respirators
- MSA Advantage 420 Half-Mask respirators
- MSA Advantage 3000 Full-Facepiece respirators
- MSA Advantage 4000 Full-Facepiece respirators
- MSA Advantage 1000 Full-Mask respirators
- All MSA Advantage Series facepieces with bayonet cartridge ports
Replaces / Drop-In Replacement For
The MSA 815366 is a direct replacement cartridge for all standard MSA Advantage Series respirator models equipped with bayonet-style cartridge ports. Verify your respirator’s cartridge connection type before ordering.
Works With
- MSA Advantage Series respiratory protection program
- NIOSH-approved respiratory protection systems
- Bayonet-connection cartridge holders and filter assemblies
- Industrial safety and compliance frameworks requiring P100 filtration








